TIGR® Matrix is the world’s first long-term resorbable, 100% synthetic, surgical mesh. Its unique technology consisting of dual-stage degradation and full resorption, paired with ease of use, is a significant step forward in surgical mesh technology. Since it uses polymers common in medical devices since the 1970’s, and is 100% synthetic, its components are more than well documented and clinically proven.
TIGR® Matrix was developed to take advantage of the process whereby mechanical load induces remodeling of soft tissue, termed dynamic remodeling. After initial wound closure, the increasing compliance of the mesh results in a gradual transition of load from the mesh to the tissue. Long-term strength retention combined with the dynamic remodeling-based design opens up new opportunities in soft tissue repair.
This design was developed to compensate optimally for the soft tissue’s lack of strength during each phase of wound-healing (closure, granulation and remodeling).1 Accordingly, the mesh degrades in several stages, each with different characteristics, described below.
Characteristic Strength and Compliance
Multistage mechanics are achieved by arranging two fibers with different degradation characteristics in an interlocking knitting pattern.
The family of polymers used in the mesh is well known in the surgical community for its resorbability and biocompatibility since the 1970s. At first glance, visually the two fibers appear quite similar, but their resorption characteristics differ significantly.
Fast Resorbing Fiber
Slow Resorbing Fiber
DEGRADATION AND RESORPTION
The following illustration shows the dynamic interaction between TIGR® Matrix and soft tissue during the different wound healing phases.
Both fibers degrade by bulk hydrolysis. After degradation the fibers are excreted by the human body through natural means. The figure below depicts these metabolic pathways.
TIGR® Matrix is sterilized with ethylene oxide (EtO) and is for single use only.
TIGR® Matrix is packed in a double-pouch system to ensure sterility and to protect it from degradation.
Inner pouch (sterile barrier)
Outer pouch (moisture barrier)